【摘要】  目的 探讨综合性神经康复治疗对偏瘫患者神经功能缺损及抑郁障碍的疗效。方法 将62例首发偏瘫伴抑郁症状的患者随机分为治疗组和对照组，每组31例，治疗组给予规范的综合性神经康复治疗，包括运动疗法、心理治疗和神经科常规药物治疗，对照组予神经科常规药物治疗。用脑卒中患者临床神经功能缺损程度评分标准和汉密尔顿抑郁量表(HAMD)，分别于治疗前和治疗后2、4周末对患者进行疗效评定。结果 治疗组与对照组脑卒中患者临床神经功能缺损程度评分和HAMD评分在治疗前差异无显著性(P>0.05);治疗2周末治疗组评分低于对照组，但差异无显著性(P>0.05);4周末治疗组评分均低于对照组，差异有显著性(P<0.05)。结论 综合性神经康复治疗能显著改善偏瘫患者神经功能缺损，缓解患者的抑郁症状。

【关键词】  偏瘫;抑郁;神经功能缺损;康复治疗

Abstract： Objective To probe into the effect of a comprehensive neurological rehabilitation regimen on the neurological impairment and remission of depression in patients with hemiplegia. Methods 62 cases of the initial hemiplegia with depression were randomized into two groups: the treatment group and the control group (n=31 ealch). The treatment group underwent standardized integral treatment of neurological rehabilitation, physical therapy, routine psychological and neurological medication; while the control group only received routine neurological drug administration. Patients with stroke were assessed for efficacy by clinical neurological impairment scoring criteria and the Hamilton Depression Rating Scale (HAMD), before treatment and 2 and 4 weeks after treatment, respectively. Results The clinical neurological impairment score and the HAMD scores had no differences between the treatment group and the control group before the treatment (P>0.05); and 2 weeks after the treatment, the scores in treatment group were slightly lower than those in the control group, but the difference had no statistical significance (P>0.05); the clinical degree of neurological impairments and HAMD scores of patients with stroke in the treatment group were lower than those in the control group, with significant statistical difference at the end of the 4th week (P<0.05). Conclusion The neurological rehabilitation therapy can significantly improve the neurological impairment and relieve the depressive symptoms in patients with hemiplegia.

Key words： hemiplegia; depression; neurological impairment; rehabilitation therapy